SCHEMBL11270600

SCHEMBL11270600

Cc1ccc(C(O)Cn2cncn2)cc1

nearest known ligand 0.72

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.49
ALDH1A1 P00352 1/20 0.49
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
CYP19A1 P11511 1/20 0.41
TSHR P16473 2/20 0.41
POLB P06746 1/20 0.40
HPGD P15428 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11273790 0.84 CYP19A1 (0.59) KMT2ACYP3A4CYP2C19CYP19A1TSHR
SCHEMBL9634892 0.84 CYP19A1 (0.50) ALDH1A1MEN1KMT2ACYP3A4CYP19A1
SCHEMBL11188697 0.84 HMOX1 (0.51) ALDH1A1MEN1KMT2ACYP19A1TSHR
SCHEMBL7783933 0.83 TSHR (0.58) ALDH1A1MEN1KMT2ACYP19A1TSHR
SCHEMBL5544140 0.83 TSHR (0.58) ALDH1A1MEN1KMT2ACYP19A1TSHR
SCHEMBL10972636 0.83 NPSR1 (0.48) NPSR1ALDH1A1MEN1KMT2ACYP1A2
SCHEMBL10957058 0.83 ALDH1A1 (0.55) ALDH1A1KMT2ACYP19A1POLBHPGD
SCHEMBL19062966 0.82 NPSR1 (0.47) NPSR1ALDH1A1MEN1KMT2ACYP1A2
SCHEMBL10999589 0.81 MEN1 (0.49) NPSR1ALDH1A1MEN1KMT2ACYP19A1
SCHEMBL11185511 0.81 CYP19A1 (0.59) CYP3A4CYP2C19CYP19A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4349556-A Pesticidally active 1-acyloxy-1-phenyl-2-azolyl-ethanes BAYER AKTIENGESELLSCHAFT (DE) 1982-09-14 US disclosed