Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 10/20 | 0.35 |
| ▸ | CDK2 | P24941 | 10/20 | 0.35 |
| ▸ | CDK3 | Q00526 | 10/20 | 0.35 |
| ▸ | GRK2 | P25098 | 6/20 | 0.35 |
| ▸ | AURKA | O14965 | 5/20 | 0.35 |
| ▸ | CDK1 | P06493 | 5/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270922 | 0.80 | ALDH1A1 (0.37) | ALDH1A1MAPTNPC1HPGDKDM4E | |
| SCHEMBL11261507 | 0.72 | CCNE1 (0.36) | CCNE1CDK2CDK3GRK2AURKA | |
| Hydrochloric Acid SCHEMBL11264345 | 0.71 | CCNE1 (0.35) | CCNE1CDK2CDK3GRK2AURKA | |
| SCHEMBL11256036 | 0.69 | KMT2A (0.38) | CCNE1CDK2CDK3GRK2AURKA | |
| SCHEMBL11270927 | 0.68 | — | — | |
| SCHEMBL11264134 | 0.68 | RAB9A (0.49) | ALDH1A1NPC1SMN1; SMN2LMNARAB9A | |
| Hydrochloric Acid SCHEMBL11255070 | 0.67 | RAB9A (0.48) | ALDH1A1NPC1SMN1; SMN2LMNARAB9A | |
| SCHEMBL11262078 | 0.63 | ALDH1A1 (0.51) | ALDH1A1MAPTNPC1HPGDKDM4E | |
| SCHEMBL11264970 | 0.63 | RAB9A (0.44) | ALDH1A1MAPTNPC1SMN1; SMN2LMNA | |
| SCHEMBL11259852 | 0.62 | ALDH1A1 (0.46) | CCNE1CDK2CDK3AURKAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |