Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270920 | 0.80 | CCNE1 (0.35) | ALDH1A1MAPTNPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL11261511 | 0.73 | MAPT (0.46) | ALDH1A1MAPTNPC1SMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL11264349 | 0.72 | MAPT (0.45) | ALDH1A1MAPTNPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL11270927 | 0.72 | — | — | |
| SCHEMBL11262749 | 0.71 | ALDH1A1 (0.41) | ALDH1A1MAPTNPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL11256038 | 0.71 | MAPT (0.41) | ALDH1A1MAPTNPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL11264138 | 0.68 | RAB9A (0.48) | ALDH1A1NPC1SMN1; SMN2HSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL11255071 | 0.67 | RAB9A (0.47) | ALDH1A1NPC1SMN1; SMN2HSD17B10LMNA | |
| SCHEMBL11264975 | 0.65 | ALDH1A1 (0.44) | ALDH1A1MAPTNPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL29360795 | 0.64 | KAT8 (0.58) | ALDH1A1MAPTNPC1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |