Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363516 | 0.74 | CYP1A2 (0.52) | KDM4ENPC1RAB9AALDH1A1PKM | |
| Metamitron SCHEMBL66369 | 0.70 | KDM4E (0.49) | KDM4ENPC1RAB9AALDH1A1PKM | |
| Metamitron SCHEMBL8536394 | 0.70 | KDM4E (0.49) | KDM4ENPC1RAB9AALDH1A1PKM | |
| SCHEMBL29126016 | 0.66 | BRD9 (0.51) | KDM4EALDH1A1SMN1; SMN2BRD4 | |
| SCHEMBL2834048 | 0.64 | GABRA1 (0.44) | KDM4EALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL30883267 | 0.64 | KDM4E (1.00) | KDM4ENPC1RAB9AALDH1A1PKM | |
| SCHEMBL11545985 | 0.64 | MASP2 (0.56) | ALDH1A1MAPTLMNA | |
| SCHEMBL1428216 | 0.64 | KDM4E (1.00) | KDM4ENPC1RAB9AALDH1A1PKM | |
| SCHEMBL9655128 | 0.62 | KDM4E (0.42) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11978674 | 0.62 | AKT1 (0.44) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067382-A2 | N-cyclohexyl-chloroacetamides, their preparation and their use in combating undesired plant growth | BASF Aktiengesellschaft (DE) | 1982-12-22 | — | — | EP | disclosed |