Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 6/20 | 0.51 |
| ▸ | NOS1 | P29475 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714691 | 0.84 | DGAT1 (0.43) | MASP2XDHNOS1ALDH1A1FGFR1 | |
| SCHEMBL7708428 | 0.82 | NOS1 (0.51) | MASP2XDHNOS1FGFR1 | |
| SCHEMBL7708406 | 0.82 | LTA4H (0.50) | XDHALDH1A1MAPT | |
| SCHEMBL28868937 | 0.79 | RECQL (0.60) | ALDH1A1MAPTUSP30 | |
| SCHEMBL13665045 | 0.74 | MASP2 (0.72) | MASP2ALDH1A1FGFR1AOC3LMNA | |
| SCHEMBL10981729 | 0.74 | LMNA (0.55) | XDHALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL725351 | 0.72 | MASP2 (1.00) | MASP2AOC3 | |
| SCHEMBL7515639 | 0.71 | TYMS (0.51) | MASP2XDHNOS1QTRT1AOC3 | |
| SCHEMBL6049582 | 0.71 | NUDT1 (0.50) | XDHFGFR1PDE3A | |
| SCHEMBL5206240 | 0.70 | NOS1 (0.45) | MASP2XDHNOS1QTRT1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171429-A | Pyrimidine to pyrimidine transformation process | RESEARCH CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |