Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.54 |
| ▸ | GABRP | O00591 | 2/20 | 0.54 |
| ▸ | GABRD | O14764 | 2/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.54 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.54 |
| ▸ | GABRE | P78334 | 2/20 | 0.54 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.54 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.54 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.54 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271098 | 1.00 | GABRA1 (0.54) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| SCHEMBL11276666 | 0.86 | CHRM1 (0.53) | LMNACCNE2CCNE1CDK2OPRK1 | |
| SCHEMBL11276681 | 0.86 | CHRM1 (0.53) | LMNACCNE2CCNE1CDK2OPRK1 | |
| SCHEMBL2971403 | 0.82 | LMNA (0.60) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| SCHEMBL29611554 | 0.79 | GABRA1 (0.61) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| SCHEMBL11467997 | 0.79 | GABRA1 (0.61) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| SCHEMBL7318731 | 0.75 | GABRA1 (0.54) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| SCHEMBL28536668 | 0.75 | GABRA1 (0.57) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| SCHEMBL10918115 | 0.73 | OPRK1 (0.54) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| SCHEMBL10918118 | 0.73 | OPRK1 (0.54) | GABRA1GABRA5GABRA3GABRA2GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004024-B1 | METHOD FOR PREPARING 3-HYDROXY-6-PHENYL-1,2,3,4-TETRAHYDRO-1,5-BENZODIAZOCINES | Kali-Chemie Pharma GmbH (DE) | 1982-02-24 | — | — | EP | disclosed |
| EP-0004024-A2 | Method for preparing 3-hydroxy-6-phenyl-1,2,3,4-tetrahydro-1,5-benzodiazocines | Kali-Chemie Pharma GmbH (DE) | 1979-09-19 | — | — | EP | disclosed |