Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.57 |
| ▸ | GABRP | O00591 | 3/20 | 0.57 |
| ▸ | GABRD | O14764 | 3/20 | 0.57 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.57 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.57 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.57 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.57 |
| ▸ | GABRE | P78334 | 3/20 | 0.57 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.57 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.57 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.57 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27533159 | 0.88 | LMNA (0.59) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL27300868 | 0.88 | GABRA1 (0.44) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL28037510 | 0.86 | OPRK1 (0.56) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL27681453 | 0.85 | GABRA1 (0.41) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL27536132 | 0.84 | GABRA1 (0.62) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL27681458 | 0.82 | GABRA1 (0.42) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL7318731 | 0.78 | GABRA1 (0.54) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL27303938 | 0.76 | PTAFR (0.42) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL28426749 | 0.76 | CHRM1 (0.59) | ALOX12SMN1; SMN2LMNACCNE2CCNE1 | |
| SCHEMBL11271083 | 0.75 | GABRA1 (0.54) | GABRA1GABRA5GABRA3GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112028844-A | Preparation method of lorazepam intermediate | 北京益民药业有限公司 | 2020-12-04 | — | — | CN | claimed |
| CN-112500359-B | Preparation method of lorazepam intermediate | 华中药业股份有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-112500359-B | Preparation method of lorazepam intermediate | 华中药业股份有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-112500359-A | Preparation method of lorazepam intermediate | 华中药业股份有限公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-112500359-A | Preparation method of lorazepam intermediate | 华中药业股份有限公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-112028844-A | Preparation method of lorazepam intermediate | 北京益民药业有限公司 | 2020-12-04 | — | — | CN | disclosed |
| CN-112028844-A | Preparation method of lorazepam intermediate | 北京益民药业有限公司 | 2020-12-04 | — | — | CN | disclosed |