SCHEMBL11271418

SCHEMBL11271418

CC(C)(CC(Cc1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46
TAAR1 Q96RJ0 3/20 0.44
CYP19A1 P11511 3/20 0.41
SIGMAR1 Q99720 2/20 0.41
ALDH1A1 P00352 1/20 0.41
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
MAPK1 P28482 1/20 0.40
SLC6A2 P23975 3/20 0.39
SLC6A4 P31645 2/20 0.39
SLC6A3 Q01959 2/20 0.39
MAOA P21397 1/20 0.39
CYP2A6 P11509 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9655500 0.82 CYP19A1 (0.43) TAAR1CYP19A1SIGMAR1SLC6A2SLC6A4
SCHEMBL146771 0.77 MTNR1A (0.55) MTNR1AMTNR1BTAAR1CYP19A1SIGMAR1
SCHEMBL28696042 0.75 MTNR1A (0.53) MTNR1AMTNR1BTAAR1CYP19A1SIGMAR1
Hydrochloric Acid SCHEMBL30185866 0.75 MTNR1A (0.53) MTNR1AMTNR1BTAAR1CYP19A1SIGMAR1
SCHEMBL1019329 0.75 RIPK1 (0.52) TAAR1ALDH1A1MAPK1SLC6A3
SCHEMBL1760733 0.74 ESR1 (0.59) MTNR1AMTNR1BTAAR1CYP19A1SIGMAR1
Magnesium Chloride Anhydrous SCHEMBL28597991 0.74 TAAR1 (0.40) TAAR1MAPK1SLC6A3
SCHEMBL839666 0.73 TAAR1 (0.47) TAAR1ALDH1A1LMNAMAPK1SLC6A3
SCHEMBL10203524 0.73 HTT (0.46) MTNR1AMTNR1BTAAR1SIGMAR1ALDH1A1
Hydrogen Peroxide SCHEMBL9456548 0.72 ESR1 (0.62) MTNR1AMTNR1BTAAR1CYP19A1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4329529-A Traction fluids for traction drive transmissions NIPPON OIL CO., LTD. (JP) 1982-05-11 US disclosed