Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024056 | 0.78 | TAAR1 (0.48) | TAAR1RIPK1MAPK1CYP3A4CYP2D6 | |
| SCHEMBL1019329 | 0.78 | RIPK1 (0.52) | TAAR1RIPK1MAPK1HRH1CACNA1F | |
| SCHEMBL6681969 | 0.74 | TAAR1 (0.54) | TAAR1RIPK1MAPK1CYP3A4CYP2D6 | |
| SCHEMBL11597386 | 0.73 | TAAR1 (0.44) | TAAR1MAPK1HRH1CACNA1FOPRK1 | |
| SCHEMBL11271418 | 0.73 | MTNR1A (0.46) | TAAR1MAPK1SLC6A3LMNAALDH1A1 | |
| Magnesium Chloride Anhydrous SCHEMBL28597991 | 0.73 | TAAR1 (0.40) | TAAR1RIPK1CNR1CNR2MAPK1 | |
| SCHEMBL28188785 | 0.72 | HTR2A (0.36) | TAAR1RIPK1HRH1CYP3A4CYP2C19 | |
| SCHEMBL9858439 | 0.72 | TAAR1 (0.47) | TAAR1MAPK1CACNA1FOPRK1CACNA1D | |
| SCHEMBL10831632 | 0.71 | TAAR1 (0.56) | TAAR1SLC6A3HTR2A | |
| SCHEMBL4399836 | 0.71 | TAAR1 (0.50) | TAAR1RIPK1MAPK1CACNA1FOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6033597-A | COMPOUNDING AGENT COMPRISING A MIXTURE OF A POLYSILOXANE HAVING AN ALKOXYSILYL GROUP; AND A SULFUR CONTAINING SILANE COUPLER. | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2000-03-07 | — | — | US | claimed |
| US-11718758-B2 | Aqueous dispersion of colored particles | MITSUBISHI PENCIL COMPANY, LIMITED (JP) | 2023-08-08 | — | — | US | disclosed |
| EP-3725854-B1 | COLORED PARTICLE AQUEOUS DISPERSION | MITSUBISHI PENCIL CO (JP) | 2023-07-05 | — | — | EP | disclosed |
| US-20210071006-A1 | AQUEOUS DISPERSION OF COLORED PARTICLES | MITSUBISHI PENCIL COMPANY, LIMITED (JP) | 2021-03-11 | — | — | US | disclosed |
| EP-3725854-A1 | COLORED PARTICLE AQUEOUS DISPERSION | MITSUBISHI PENCIL COMPANY, LIMITED (JP) | 2020-10-21 | — | — | EP | disclosed |
| US-8142767-B2 | Cosmetic hair composition | MOMENTIVE PERFORMANCE MATERIALS JAPAN LLC (JP) | 2012-03-27 | — | — | US | disclosed |
| US-20100310618-A1 | COSMETIC HAIR COMPOSITION | GE TOSHIBA SILICONES CO., LTD | 2010-12-09 | — | — | US | disclosed |
| US-20070122369-A1 | Cosmetic hair composition | GE TOSHIBA SILICONES CO., LTD | 2007-05-31 | — | — | US | disclosed |
| EP-1702974-A1 | COSMETIC HAIR COMPOSITION | GE TOSHIBA SILICONES CO., LTD. (JP) | 2006-09-20 | — | — | EP | disclosed |
| JP-2004256660-A | NOVEL POLYORGANOSILOXANE AND ITS PRODUCTION METHOD | GE TOSHIBA SILICONES CO LTD | 2004-09-16 | — | — | JP | disclosed |
| JP-2004256661-A | POLYETHER-MODIFIED POLYORGANOSILOXANE, ITS PRODUCTION METHOD, AND SKIN COSMETIC | GE TOSHIBA SILICONES CO LTD | 2004-09-16 | — | — | JP | disclosed |
| EP-0761748-B1 | Polysiloxane-containing rubber composition | YOKOHAMA RUBBER CO LTD (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6525110-B1 | Silica containing vulcanizing rubber for tire treads; improved processability; low heat generation, abrasion resistance | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2003-02-25 | — | — | US | disclosed |
| US-6337361-B1 | RUBBER WITH SILICA, SILANE COUPLER AND INERT POWDER | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2002-01-08 | — | — | US | disclosed |
| US-6177505-B1 | IMPROVES THE PROCESSABILITY OF THE UNVULCANIZED RUBBER COMPOSITION, WITHOUT SUBSTANTIALLY IMPAIRING THE PROPERTIES OF THE SILICA-CONTAINING VULCANIZING RUBBER COMPOSITION | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2001-01-23 | — | — | US | disclosed |
| US-6121347-A | A REINFORCING FILLER COMPRISING INERT POWDER COUPLED WITH A SILANE COUPLING AGENT TO A POLYSILOXANE RESIN OR A SILOXANE COMPOUND; IMPROVING LOW HEAT GENERATION, THE MODULUS AND THE ABRASION RESISTANCE OF THE RUBBER | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2000-09-19 | — | — | US | disclosed |
| US-6033597-A | COMPOUNDING AGENT COMPRISING A MIXTURE OF A POLYSILOXANE HAVING AN ALKOXYSILYL GROUP; AND A SULFUR CONTAINING SILANE COUPLER. | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2000-03-07 | — | — | US | disclosed |
| EP-0761748-A2 | Polysiloxane-containing rubber composition | THE YOKOHAMA RUBBER CO., LTD. (JP) | 1997-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100310618-A1 | COSMETIC HAIR COMPOSITION | POLR1C, CUTA, PIK3C3 | TAAR1 693/4885RIPK1 3306/4885CNR1 3746/4885 |
| US-20070122369-A1 | Cosmetic hair composition | POLR1C, CUTA, PIK3C3 | TAAR1 693/4885RIPK1 3306/4885CNR1 3746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.