Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272940 | 0.90 | LMNA (0.58) | ABCB11LMNAMAPTMAPK1SIGMAR1 | |
| SCHEMBL11269045 | 0.89 | MAPT (0.57) | ABCB11LMNAMAPTMAPK1SIGMAR1 | |
| SCHEMBL11292589 | 0.86 | LMNA (0.65) | ABCB11LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL11267381 | 0.85 | MAPT (0.55) | ABCB11LMNAMAPTMAPK1SIGMAR1 | |
| SCHEMBL11135851 | 0.83 | ABCB11 (0.44) | ABCB11LMNAMAPTMAPK1SIGMAR1 | |
| SCHEMBL11268845 | 0.81 | LMNA (0.61) | ABCB11LMNAMAPTMAPK1HDAC6 | |
| SCHEMBL11274582 | 0.80 | ABCB11 (0.53) | ABCB11LMNAMAPTMAPK1L3MBTL1 | |
| SCHEMBL11261344 | 0.80 | TSHR (0.46) | ABCB11LMNAMAPTMAPK1SIGMAR1 | |
| SCHEMBL11261223 | 0.79 | ABCB11 (0.59) | ABCB11LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL11276117 | 0.79 | MAPT (0.44) | ABCB11LMNAMAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |