Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272940 | 0.99 | LMNA (0.58) | MAPTLMNAMAPK1ABCB11SMN1; SMN2 | |
| SCHEMBL11267381 | 0.96 | MAPT (0.55) | MAPTLMNAMAPK1ABCB11SMN1; SMN2 | |
| SCHEMBL11271824 | 0.89 | ABCB11 (0.53) | MAPTLMNAMAPK1ABCB11SMN1; SMN2 | |
| SCHEMBL4731655 | 0.85 | LMNA (0.72) | MAPTLMNAMAPK1ABCB11SMN1; SMN2 | |
| SCHEMBL11268901 | 0.85 | LMNA (0.72) | MAPTLMNAMAPK1ABCB11SMN1; SMN2 | |
| SCHEMBL11261344 | 0.84 | TSHR (0.46) | MAPTLMNAMAPK1ABCB11SMN1; SMN2 | |
| SCHEMBL11264433 | 0.83 | LMNA (0.68) | MAPTLMNAMAPK1ABCB11SMN1; SMN2 | |
| SCHEMBL11295543 | 0.82 | LMNA (0.75) | MAPTLMNAMAPK1ABCB11SMN1; SMN2 | |
| SCHEMBL960224 | 0.81 | LMNA (0.77) | MAPTLMNAMAPK1ABCB11SMN1; SMN2 | |
| SCHEMBL11208472 | 0.81 | SMN1; SMN2 (0.43) | MAPTLMNAMAPK1ABCB11SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |