Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127445 | 0.90 | TRPV1 (0.39) | ALDH1A1LMNAKDM4ETRPV1MAPT | |
| SCHEMBL1126932 | 0.88 | MAPT (0.38) | ALDH1A1LMNATRPV1MAPTGAA | |
| SCHEMBL1126527 | 0.87 | MAPT (0.37) | ALDH1A1LMNATRPV1MAPTGAA | |
| SCHEMBL1126898 | 0.86 | TRPV1 (0.41) | ALDH1A1LMNAKDM4ETRPV1MAPT | |
| SCHEMBL1127265 | 0.86 | KDR (0.37) | ALDH1A1LMNATRPV1MAPTGAA | |
| SCHEMBL1127185 | 0.85 | MALT1 (0.37) | ALDH1A1TRPV1MAPTGAAPOLB | |
| SCHEMBL1988343 | 0.84 | DRD2 (0.38) | MCHR1HTR1ADRD2ALDH1A1LMNA | |
| SCHEMBL1127448 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNATRPV1MAPTGAA | |
| SCHEMBL1127076 | 0.81 | TRPV1 (0.38) | ALDH1A1LMNATRPV1MAPTGAA | |
| SCHEMBL1647342 | 0.79 | MAPT (0.40) | ALDH1A1LMNAKDM4ETRPV1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |