Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 7/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11295722 | 0.78 | NPC1 (0.34) | NPC1RAB9ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL11272042 | 0.78 | NPC1 (0.38) | NPC1RAB9ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL11301700 | 0.75 | TP53 (0.38) | NPC1RAB9ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL11273014 | 0.71 | PLA2G10 (0.36) | LMNAKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL11283398 | 0.66 | TP53 (0.40) | NPC1RAB9ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL11273016 | 0.62 | ALDH1A1 (0.36) | LMNAKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL11276788 | 0.60 | SMN1; SMN2 (0.34) | KDM4ESMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL11283401 | 0.60 | LMNA (0.35) | NPC1RAB9ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL27259333 | 0.58 | LTA4H (0.46) | NPC1RAB9ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL27259421 | 0.56 | RAB9A (0.49) | NPC1RAB9ALMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338326-A | PESTICIDES | UNION CARBIDE CORPORATION (US) | 1982-07-06 | — | — | US | disclosed |