Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | IL2 | P60568 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270873 | 0.90 | MAPK14 (0.46) | NPY5RPTGESCCR1NPBWR1MCHR1 | |
| SCHEMBL11275261 | 0.87 | TLR7 (0.51) | MEN1KMT2APTGESALDH1A1MAPT | |
| SCHEMBL11286892 | 0.86 | RXFP1 (0.48) | NPY5RCCR1NPBWR1MCHR1SMN1; SMN2 | |
| SCHEMBL11286418 | 0.84 | RXFP1 (0.46) | NPY5RMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11273156 | 0.81 | MAPK14 (0.49) | NPY5RKMT2ACCR1NPBWR1MCHR1 | |
| SCHEMBL11274203 | 0.79 | TLR7 (0.52) | MEN1KMT2APTGESALDH1A1NPBWR1 | |
| SCHEMBL11271650 | 0.78 | RXFP1 (0.46) | NPY5RKMT2ACCR1NPBWR1MCHR1 | |
| SCHEMBL9135913 | 0.77 | GAA (0.45) | MEN1KMT2ALMNAALDH1A1CCR1 | |
| SCHEMBL11283145 | 0.76 | MAPK14 (0.47) | NPY5RMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL3039672 | 0.74 | MAPT (0.61) | MEN1KMT2ALMNAALDH1A1NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | claimed |
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |