Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 5/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276599 | 0.93 | TLR7 (0.43) | MAPK14NPBWR1MCHR1CCR1PKM | |
| SCHEMBL11270873 | 0.91 | MAPK14 (0.46) | MAPK14NPBWR1MCHR1CCR1MAPT | |
| SCHEMBL11283145 | 0.91 | MAPK14 (0.47) | MAPK14NPBWR1MCHR1CCR1PKM | |
| SCHEMBL11274203 | 0.88 | TLR7 (0.52) | NPBWR1MCHR1KMT2AMAPT | |
| SCHEMBL11271650 | 0.85 | RXFP1 (0.46) | MAPK14NPBWR1MCHR1CCR1PKM | |
| SCHEMBL11273766 | 0.85 | SMN1; SMN2 (0.47) | MAPK14PKMKMT2ASMN1; SMN2MAPT | |
| SCHEMBL11278901 | 0.84 | HTT (0.46) | MAPK14PKMKMT2ASMN1; SMN2MAPT | |
| SCHEMBL11275106 | 0.83 | NPY5R (0.45) | MAPK14NPBWR1MCHR1CCR1KMT2A | |
| SCHEMBL8669219 | 0.83 | GAA (0.46) | NPBWR1MCHR1CCR1MAPT | |
| SCHEMBL11286418 | 0.82 | RXFP1 (0.46) | MAPK14NPBWR1MCHR1CCR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | claimed |
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |