Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276599 | 0.94 | TLR7 (0.43) | TLR7GAAPTGESMEN1KMT2A | |
| SCHEMBL11275261 | 0.92 | TLR7 (0.51) | TLR7GAAPTGESMEN1KMT2A | |
| SCHEMBL11273156 | 0.88 | MAPK14 (0.49) | KMT2AMAPTNPBWR1MCHR1 | |
| SCHEMBL8669219 | 0.86 | GAA (0.46) | GAAKDM4ENPC1MAPTRORC | |
| SCHEMBL11273766 | 0.82 | SMN1; SMN2 (0.47) | PTGESMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11283145 | 0.81 | MAPK14 (0.47) | GAAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11273034 | 0.81 | SMN1; SMN2 (0.41) | GAAKMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL11270873 | 0.80 | MAPK14 (0.46) | PTGESMAPTNPBWR1MCHR1 | |
| SCHEMBL11278901 | 0.79 | HTT (0.46) | PTGESMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11279223 | 0.79 | MEN1 (0.48) | TLR7GAAPTGESMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | claimed |
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |