Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274203 | 0.92 | TLR7 (0.52) | TLR7PTGESGAATLR8KDM4E | |
| SCHEMBL11270873 | 0.88 | MAPK14 (0.46) | PTGESMAPT | |
| SCHEMBL9135913 | 0.87 | GAA (0.45) | GAANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL11272082 | 0.87 | NPY5R (0.45) | PTGESNPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL11276599 | 0.86 | TLR7 (0.43) | TLR7PTGESGAATLR8KDM4E | |
| SCHEMBL11286418 | 0.81 | RXFP1 (0.46) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11273156 | 0.80 | MAPK14 (0.49) | KMT2AMAPT | |
| SCHEMBL8669219 | 0.78 | GAA (0.46) | GAAKDM4ENPC1MAPTRORC | |
| SCHEMBL11273034 | 0.76 | SMN1; SMN2 (0.41) | GAAKDM4ENPC1ALDH1A1KMT2A | |
| SCHEMBL11286892 | 0.75 | RXFP1 (0.48) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | claimed |
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |