Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127257 | 0.90 | GAA (0.38) | ALDH1A1TSHRKDRGAATRPV1 | |
| SCHEMBL1127448 | 0.83 | ALDH1A1 (0.39) | ALDH1A1TSHRKDRGAATRPV1 | |
| SCHEMBL1127445 | 0.82 | TRPV1 (0.39) | ALDH1A1TSHRKDM4EGAATRPV1 | |
| SCHEMBL1987403 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TSHRKDM4EGAANPY2R | |
| SCHEMBL1127265 | 0.80 | KDR (0.37) | ALDH1A1TSHRKDRGAATRPV1 | |
| SCHEMBL1126898 | 0.80 | TRPV1 (0.41) | ALDH1A1KDM4EKDRGAATRPV1 | |
| SCHEMBL1127072 | 0.79 | MALT1 (0.39) | ALDH1A1TSHRKDM4EKDRFPR2 | |
| SCHEMBL1126932 | 0.79 | MAPT (0.38) | ALDH1A1TSHRKDRGAATRPV1 | |
| SCHEMBL1127076 | 0.78 | TRPV1 (0.38) | ALDH1A1TSHRGAATRPV1NPY2R | |
| SCHEMBL1126527 | 0.78 | MAPT (0.37) | ALDH1A1TSHRGAATRPV1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |