Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ME2 | P23368 | 1/20 | 0.34 |
| ▸ | ME1 | P48163 | 1/20 | 0.34 |
| ▸ | ME3 | Q16798 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127209 | 0.90 | ALDH1A1 (0.40) | GAATRPV1KDRALDH1A1MAPT | |
| SCHEMBL1127445 | 0.82 | TRPV1 (0.39) | GAATRPV1ALDH1A1MAPTPOLB | |
| SCHEMBL1126898 | 0.81 | TRPV1 (0.41) | GAATRPV1KDRALDH1A1MAPT | |
| SCHEMBL1126410 | 0.81 | MEN1 (0.39) | GAAALDH1A1MAPTPOLBHSD17B10 | |
| SCHEMBL1127072 | 0.80 | MALT1 (0.39) | GAATRPV1KDRALDH1A1MAPT | |
| SCHEMBL1126932 | 0.79 | MAPT (0.38) | GAATRPV1KDRALDH1A1MAPT | |
| SCHEMBL1127448 | 0.78 | ALDH1A1 (0.39) | GAATRPV1KDRALDH1A1MAPT | |
| SCHEMBL1126527 | 0.78 | MAPT (0.37) | GAATRPV1ALDH1A1MAPTPOLB | |
| SCHEMBL1127332 | 0.77 | MCHR1 (0.39) | GAATRPV1ALDH1A1MAPTPOLB | |
| SCHEMBL1127265 | 0.77 | KDR (0.37) | GAATRPV1KDRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | claimed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | claimed |