Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | HCK | P08631 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126519 | 0.82 | F10 (0.41) | MALT1MAPKAPK2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1127257 | 0.80 | GAA (0.38) | TRPV1MAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL1127209 | 0.79 | ALDH1A1 (0.40) | TRPV1MAPTALDH1A1TSHRKDR | |
| SCHEMBL1127185 | 0.77 | MALT1 (0.37) | MALT1TRPV1MAPTALDH1A1TSHR | |
| SCHEMBL1126697 | 0.74 | MALT1 (0.41) | MALT1MAPTALDH1A1TSHRLMNA | |
| SCHEMBL1126898 | 0.74 | TRPV1 (0.41) | MALT1TRPV1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1126674 | 0.74 | LMNA (0.38) | MALT1MAPTALDH1A1TSHRLMNA | |
| SCHEMBL1127445 | 0.73 | TRPV1 (0.39) | MALT1TRPV1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1127076 | 0.73 | TRPV1 (0.38) | MALT1TRPV1MAPTALDH1A1TSHR | |
| SCHEMBL1126932 | 0.72 | MAPT (0.38) | MALT1TRPV1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | claimed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | claimed |