Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.41 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8209789 | 0.92 | TP53 (0.51) | TP53POLBKMT2ALMNAMAPT | |
| SCHEMBL18926552 | 0.90 | PSMD10 (0.45) | TP53KMT2APSMD10CYP24A1VDR | |
| SCHEMBL18926562 | 0.84 | CNR2 (0.44) | KMT2APSMD10CYP24A1VDRMEN1 | |
| SCHEMBL7655861 | 0.83 | ALDH1A1 (0.46) | POLBKMT2ALMNAMAPTPSMD10 | |
| SCHEMBL7324405 | 0.83 | MGLL (0.44) | POLBKMT2ALMNAMAPTPSMD10 | |
| SCHEMBL5870554 | 0.82 | TP53 (0.53) | TP53POLBKMT2ALMNAMAPT | |
| SCHEMBL7028389 | 0.80 | CNR2 (0.50) | LMNAPSMD10CYP24A1L3MBTL1ALDH1A1 | |
| SCHEMBL23727436 | 0.80 | LMNA (0.45) | POLBKMT2ALMNAPSMD10CYP24A1 | |
| SCHEMBL30125726 | 0.80 | LMNA (0.45) | POLBKMT2ALMNAPSMD10CYP24A1 | |
| SCHEMBL5098194 | 0.79 | ALDH1A1 (0.45) | LMNAALDH1A1HPGDTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |