SCHEMBL5870554

SCHEMBL5870554

Cc1ccc(S(=O)(=O)OCc2ccccc2Cl)cc1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.53
POLB P06746 2/20 0.48
KMT2A Q03164 3/20 0.47
LMNA P02545 1/20 0.47
PLA2G1B P04054 1/20 0.45
PKM P14618 1/20 0.45
ATG4B Q9Y4P1 1/20 0.45
IDO1 P14902 2/20 0.43
TAS2R14 Q9NYV8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
VDR P11473 1/20 0.42
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8061919 0.89 VDR (0.47) TP53KMT2ALMNAL3MBTL1VDR
SCHEMBL28243715 0.87 IDO1 (0.48) IDO1L3MBTL1MAPTALDH1A1
SCHEMBL7542901 0.86 IDO1 (0.44) TP53POLBIDO1L3MBTL1MAPT
SCHEMBL8209789 0.85 TP53 (0.51) TP53POLBKMT2ALMNAPLA2G1B
SCHEMBL19207382 0.84 ALDH1A1 (0.42) TP53POLBKMT2APKMVDR
SCHEMBL5870619 0.84 MEN1 (0.54) TP53KMT2APKMVDRMEN1
SCHEMBL13954243 0.84 VDR (0.51) TP53POLBKMT2ALMNAL3MBTL1
SCHEMBL31233473 0.83 GAA (0.42) TP53KMT2ALMNAVDRMEN1
SCHEMBL11272133 0.82 TP53 (0.49) TP53POLBKMT2ALMNAPLA2G1B
SCHEMBL7542998 0.82 IDO1 (0.41) TP53POLBKMT2ALMNAIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7001973-B2 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2006-02-21 US claimed
CN-116947743-A Nitrosothiol compound and synthesis method and application thereof 南京雷正医药科技有限公司 2023-10-27 CN disclosed
US-7001973-B2 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2006-02-21 US disclosed
US-20030187178-A1 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2003-10-02 US disclosed
US-6613863-B2 Benzyltrialkylammonium carboxylate isocyanate trimerization catalysts DEGUSSA AG (DE) 2003-09-02 US disclosed
US-20020120089-A1 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2002-08-29 US disclosed
US-4557753-A Herbicidal 4-benzoyl-1-methyl-5-phenylalkoxy pyrazoles NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1985-12-10 US disclosed