SCHEMBL1127221

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1987843	0.81	NPC1 (0.49)	POLBMAPK1LMNAALDH1A1MAPT
	SCHEMBL1645588	0.80	CYP1A2 (0.71)	POLBLMNAALDH1A1MAPTKMT2A
	SCHEMBL2231864	0.79	POLB (0.47)	POLBMAPK1ALDH1A1MAPTKMT2A
	SCHEMBL1645589	0.78	MAPT (0.46)	POLBMAPK1LMNAALDH1A1MAPT
	SCHEMBL1645614	0.78	NPC1 (0.56)	POLBMAPK1LMNAALDH1A1MAPT
	SCHEMBL15306485	0.77	KMT2A (0.56)	MAPK1LMNAALDH1A1MAPTKMT2A
	SCHEMBL9665242	0.73	MAPK1 (0.70)	MAPK1LMNAALDH1A1MAPTCYP1A2
	SCHEMBL27560077	0.73	TSHR (0.56)	LMNAALDH1A1MAPTKMT2AMEN1
	SCHEMBL22022017	0.72	LMNA (0.65)	LMNAALDH1A1MAPTKMT2AMEN1
	SCHEMBL9077089	0.72	MAPK1 (0.83)	MAPK1LMNAALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.