Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5737722 | 0.81 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1TRPA1KMT2APOLB | |
| SCHEMBL10395011 | 0.79 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1TRPA1KMT2APOLB | |
| SCHEMBL8148446 | 0.79 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1TRPA1KMT2APOLB | |
| SCHEMBL10676780 | 0.79 | TSHR (0.50) | L3MBTL1ALDH1A1KMT2AGAAMGAM | |
| SCHEMBL10682900 | 0.79 | TSHR (0.50) | L3MBTL1ALDH1A1KMT2AGAAMGAM | |
| SCHEMBL10676771 | 0.79 | TSHR (0.50) | L3MBTL1ALDH1A1KMT2AGAAMGAM | |
| SCHEMBL2001692 | 0.79 | ALDH1A1 (0.39) | ALDH1A1CYP1A2LMNA | |
| SCHEMBL11004191 | 0.78 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1TRPA1KMT2APOLB | |
| SCHEMBL8154344 | 0.78 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1TRPA1KMT2APOLB | |
| SCHEMBL11076712 | 0.78 | CYP1A2 (0.56) | L3MBTL1ALDH1A1TRPA1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329363-A | Substituted mercapto acid amides and their use | MERCK & CO., INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4216160-A | IMMUNOREGULANTS FOR CORRECTING AN INBALANCE OF IMMUNE HOMEOSTASIS | MERCK & CO., INC. (US) | 1980-08-05 | — | — | US | disclosed |
| EP-0001989-A1 | Substituted mercapto acid amides, process for their preparation, pharmaceutical composition containing same and their use | MERCK & CO. INC. (US) | 1979-05-30 | — | — | EP | disclosed |