SCHEMBL1127288

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126369	0.83	L3MBTL1 (0.80)	L3MBTL1RAB9AMAPTLMNATDP1
	SCHEMBL1126545	0.80	L3MBTL1 (1.00)	L3MBTL1RAB9AMAPTLMNATDP1
	SCHEMBL1126436	0.78	L3MBTL1 (0.81)	L3MBTL1RAB9AMAPTLMNATDP1
	SCHEMBL1126417	0.78	L3MBTL1 (0.81)	L3MBTL1RAB9AMAPTLMNATDP1
	SCHEMBL1126455	0.77	L3MBTL1 (0.64)	L3MBTL1RAB9AMAPTLMNATDP1
	SCHEMBL1126500	0.76	CYP3A4 (0.80)	L3MBTL1RAB9AMAPTLMNATDP1
	SCHEMBL1126679	0.74	RAB9A (1.00)	RAB9AMAPTCYP3A4SMN1; SMN2ALDH1A1
	SCHEMBL24754704	0.67	RAB9A (0.56)	RAB9ALMNACYP3A4SMN1; SMN2ALDH1A1
	SCHEMBL20825514	0.66	KMT2A (0.50)	L3MBTL1MAPTLMNASMN1; SMN2ALDH1A1
	SCHEMBL8875381	0.64	MAPT (0.58)	RAB9AMAPTLMNASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.