Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274203 | 0.94 | TLR7 (0.52) | TLR7NPBWR1MCHR1MAPTNPC1 | |
| SCHEMBL11273156 | 0.93 | MAPK14 (0.49) | NPBWR1MCHR1MAPK14MAPTKMT2A | |
| SCHEMBL8669219 | 0.89 | GAA (0.46) | NPBWR1MCHR1MAPTNPSR1NPC1 | |
| SCHEMBL11273766 | 0.88 | SMN1; SMN2 (0.47) | MAPK14MAPTNPSR1NPC1RAB9A | |
| SCHEMBL11275261 | 0.86 | TLR7 (0.51) | TLR7MAPTNPC1GAAKMT2A | |
| SCHEMBL11270873 | 0.85 | MAPK14 (0.46) | NPBWR1MCHR1MAPK14MAPTPTGES | |
| SCHEMBL11278901 | 0.84 | HTT (0.46) | MAPK14MAPTNPSR1NPC1RAB9A | |
| SCHEMBL11273034 | 0.84 | SMN1; SMN2 (0.41) | NPBWR1MCHR1MAPTNPSR1NPC1 | |
| SCHEMBL11283145 | 0.84 | MAPK14 (0.47) | NPBWR1MCHR1MAPK14MAPTGAA | |
| SCHEMBL11277938 | 0.83 | PTGES (0.52) | NPBWR1MAPTNPSR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | claimed |
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |