Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265484 | 0.92 | ALDH1A1 (0.36) | ROCK2PPARDPPARAPPARGMAPT | |
| SCHEMBL11266860 | 0.85 | PPARD (0.35) | ROCK2PPARDPPARAPPARGMGLL | |
| SCHEMBL11270305 | 0.85 | MAPT (0.39) | PPARDPPARAPPARGMGLLPTGS2 | |
| SCHEMBL11273387 | 0.83 | MEN1 (0.38) | PPARDPPARAPPARGPTGS2MEN1 | |
| SCHEMBL11279667 | 0.80 | MAPT (0.46) | PPARDPPARAPPARGMGLLPTGS2 | |
| SCHEMBL11268398 | 0.80 | ALDH1A1 (0.41) | ROCK2PPARDPPARAPPARGMAPT | |
| SCHEMBL11262022 | 0.79 | KMT2A (0.42) | MEN1KMT2APTGS1MAPT | |
| SCHEMBL11271704 | 0.79 | HTT (0.51) | PPARDPPARAPPARGMAPT | |
| SCHEMBL11276254 | 0.78 | HCAR1 (0.40) | MGLL | |
| SCHEMBL11279186 | 0.78 | SMN1; SMN2 (0.42) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350701-A | 1-(Trihalomethyl-sulfenyl)-4-aryl-1,2,4-triazolin-5-ones, and process for controlling fungi | BASF AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | disclosed |