Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279347 | 0.89 | MAPT (0.47) | MAPTHSD17B3NPBWR1PPARDPPARA | |
| SCHEMBL11273387 | 0.85 | MEN1 (0.38) | NPBWR1PPARDPPARAPPARGHCAR1 | |
| SCHEMBL11264715 | 0.84 | PPARD (0.40) | MAPTPPARDPPARAPPARGPTGS2 | |
| SCHEMBL11266860 | 0.83 | PPARD (0.35) | PPARDPPARAPPARGHCAR1PTGS1 | |
| SCHEMBL11270305 | 0.83 | MAPT (0.39) | MAPTPPARDPPARAPPARGPTGS1 | |
| SCHEMBL11265484 | 0.82 | ALDH1A1 (0.36) | MAPTPPARDPPARAPPARGHCAR1 | |
| SCHEMBL11263658 | 0.82 | PTGS2 (0.40) | MAPTPPARDPPARAPPARGPTGS1 | |
| SCHEMBL11266444 | 0.82 | ALDH1A1 (0.41) | MAPTNPBWR1PPARDPPARAPPARG | |
| SCHEMBL11273409 | 0.80 | ROCK2 (0.41) | MAPTPPARDPPARAPPARGPTGS1 | |
| SCHEMBL11260766 | 0.80 | PTGS2 (0.36) | NPBWR1PPARDPPARAPPARGPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350701-A | 1-(Trihalomethyl-sulfenyl)-4-aryl-1,2,4-triazolin-5-ones, and process for controlling fungi | BASF AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | claimed |