Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | CD69 | Q07108 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281830 | 0.84 | CD69 (0.34) | KDM4ECYP1A2MAPTEGLN1CD69 | |
| SCHEMBL4051989 | 0.78 | ALDH1A1 (0.41) | KDM4EMAPTEGLN1TDP1ABCC4 | |
| SCHEMBL4054428 | 0.76 | CDC25B (0.37) | CDC25BTDP1 | |
| SCHEMBL27883628 | 0.75 | MAOA (0.47) | CD69AKR1B1TDP1DUSP3PTPN5 | |
| SCHEMBL11282810 | 0.74 | AKR1B1 (0.34) | KDM4ECYP1A2MAPTCD69AKR1B1 | |
| SCHEMBL4056294 | 0.72 | LMNA (0.41) | KDM4EMAPT | |
| SCHEMBL10701726 | 0.71 | PDE10A (0.43) | CYP1A2MAPTTDP1 | |
| SCHEMBL30275479 | 0.71 | GLA (0.45) | CD69AKR1B1TDP1DUSP3PTPN5 | |
| SCHEMBL2197993 | 0.68 | MAOA (0.53) | CYP1A2CDC25BTDP1ABCC4PTGS1 | |
| SCHEMBL11147053 | 0.67 | KDM4E (0.65) | KDM4ECYP1A2MAPTEGLN1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124713-A | Oxopyridobenzoxepin-acetic acids and derivatives thereof useful as antiinflammatory and analgesic agents | AMERICAN HOECHST CORPORATION (US) | 1978-11-07 | — | — | US | claimed |
| US-4345087-A | Process for preparing heteroarylbenzoxepin-acetic acids, precursors and derivatives thereof | AMERICAN HOECHST CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| US-4117152-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | AMERICAN HOECHST CORPORATION (US) | 1978-09-26 | — | — | US | disclosed |
| US-4107321-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | AMERICAN HOECHST CORPORATION (US) | 1978-08-15 | — | — | US | disclosed |
| US-4107177-A | CYCLIZING (CARBOXYTHIENYLOXY)BENZENEACETIC ACID WITH DEHYDRATING AGENT | AMERICAN HOECHST CORPORATION (US) | 1978-08-15 | — | — | US | disclosed |
| US-4101559-A | ANTIINFLAMMATORY, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1978-07-18 | — | — | US | disclosed |
| US-4081457-A | ANTIINFLAMMATORY, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1978-03-28 | — | — | US | disclosed |
| US-4025640-A | ANTIINFLAMMATORY, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |