Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.35 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.35 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.35 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054428 | 0.82 | CDC25B (0.37) | MEN1KMT2AS100A4HKDC1PADI1 | |
| SCHEMBL4051989 | 0.78 | ALDH1A1 (0.41) | MAPTKDM4EMEN1KMT2AHPGD | |
| SCHEMBL10027992 | 0.76 | CYP19A1 (0.42) | LMNAMAPTMEN1NPC1RAB9A | |
| SCHEMBL4140771 | 0.76 | CA12 (0.54) | MAPTCA12CA9KDM4EMEN1 | |
| SCHEMBL10701726 | 0.74 | PDE10A (0.43) | LMNAMAPTPOLBMEN1NPC1 | |
| SCHEMBL11273607 | 0.72 | KDM4E (0.44) | MAPTKDM4E | |
| SCHEMBL2197993 | 0.71 | MAOA (0.53) | MEN1KMT2AS100A4 | |
| SCHEMBL5758407 | 0.71 | MAOB (0.53) | MAPTCA12CA9KDM4EMEN1 | |
| SCHEMBL10702167 | 0.70 | DRD2 (0.36) | LMNACYP19A1AADAT | |
| SCHEMBL10699647 | 0.70 | LMNA (0.36) | LMNAMAPTTP53KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | disclosed |
| EP-0270692-A1 | ANTIARRHYTHMIC AGENT | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1988-06-15 | — | — | EP | disclosed |