SCHEMBL1127385

SCHEMBL1127385

CC/C(C(=O)O)=C(\C)NC

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.36
FFAR3 O14843 1/20 0.36
ALDH1A1 P00352 1/20 0.36
THRB P10828 1/20 0.34
FNTA P49354 1/20 0.34
FNTB P49356 1/20 0.34
PGGT1B P53609 1/20 0.34
GRIK1 P39086 2/20 0.33
GRIA4 P48058 1/20 0.33
GRIK3 Q13003 1/20 0.33
GRIK5 Q16478 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1127391 1.00 TDP1 (0.36) TDP1FFAR3ALDH1A1THRBFNTA
Dimethylamine SCHEMBL10973447 0.78 FFAR3 (0.44) TDP1FFAR3ALDH1A1THRBFNTA
SCHEMBL6265353 0.78 ALDH1A1 (0.35) TDP1FFAR3ALDH1A1THRBFNTA
SCHEMBL5143664 0.78 FFAR3 (0.35) TDP1FFAR3ALDH1A1THRBFNTA
SCHEMBL14600824 0.78 TDP1 (0.35) TDP1ALDH1A1
SCHEMBL27684567 0.78 FFAR3 (0.50) TDP1FFAR3ALDH1A1THRBFNTA
SCHEMBL2139834 0.78 FFAR3 (0.50) TDP1FFAR3ALDH1A1THRBFNTA
SCHEMBL2094656 0.77 FFAR3 (0.45) TDP1FFAR3ALDH1A1THRBFNTA
SCHEMBL14094993 0.75 FFAR3 (0.36) TDP1FFAR3ALDH1A1THRBFNTA
SCHEMBL1509771 0.75 EPHX1 (0.34) TDP1FFAR3ALDH1A1THRBFNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9669243-B2 Delivery of hydrophobic benefit agents from bodywashes and the like onto a keratinous substrate BASF SE (DE) 2017-06-06 US disclosed
WO-2012024652-A3 SYSTEM AND METHODS FOR IMPROVED EFFICIENCY COMPRESSION IGNITION INTERNAL COMBUSTION ENGINE CONTROL TULA TECHNOLOGY, INC. (US) 2012-05-10 WO disclosed
EP-2282716-A2 DELIVERY OF HYDROPHOBIC BENEFIT AGENTS FROM BODYWASHES AND THE LIKE ONTO A KERATINOUS SUBSTRATE BASF SE (DE) 2011-02-16 EP disclosed
US-20100135936-A1 Delivery of hydrophobic benefit agents from bodywashes and the like onto a keratinous substrate BASF SE (DE) 2010-06-03 US disclosed
EP-2152230-A2 SUNSCREEN COMPOSTIONS COMPRISING A RANDOM TERPOLYMER BASF SE (DE) 2010-02-17 EP disclosed
EP-2129363-A2 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A SELECT COPOLYMER BASF SE (DE) 2009-12-09 EP disclosed
WO-2009130144-A2 DELIVERY OF HYDROPHOBIC BENEFIT AGENTS FROM BODYWASHES AND THE LIKE ONTO A KERATINOUS SUBSTRATE BASF SE (DE) 2009-10-29 WO disclosed
WO-2008122516-A2 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A SELECT COPOLYMER BASF SE (CH) 2008-10-16 WO disclosed
WO-2008122517-A2 SUNSCREEN COMPOSITIONS COMPRISING A RANDOM TERPOLYMER BASF SE (CH) 2008-10-16 WO disclosed
US-20080247975-A1 Sunscreen and personal care compositions comprising a select copolymer CIBA CORP. 2008-10-09 US disclosed
EP-0893119-B1 UV-protection formulation CIBA SC HOLDING AG (CH) 2003-09-03 EP disclosed
EP-1089706-B1 SUN SCREEN FORMULATIONS CIBA SC HOLDING AG (CH) 2003-05-02 EP disclosed
US-6521217-B1 Pulverizating cosmetic carriers and ultraviolet radiation absorbers comprising triazines, amides, benzotriazoles or benzimidazoles, in water in oil or an oil-in-water emulsions to form protective coatings or suntan lotions CIBA SPECIALTY CHEMICALS CORPORATION 2003-02-18 US disclosed
EP-1187598-A1 MICROPIGMENT MIXTURE Ciba SC Holding AG (CH) 2002-03-20 EP disclosed
US-6235271-B1 A SUNSCREEN AGENT COMPRISING A MICRONIZED ORGANIC ULTRAVIOLET ABSORBER, AN OIL SOLUBLE, NON-MICRONIZED ULTRAVIOLET ABSORBER AND/OR INORGANIC MICROPIGMENT AND A COPOLYMER OF ACRYLIC ACID-STYRENE AS HOLLOW SPHERE CIBA SPECIALTY CHEMICALS CORPORATION 2001-05-22 US disclosed
EP-1089706-A1 SUN SCREEN FORMULATIONS Ciba SC Holding AG (CH) 2001-04-11 EP disclosed
EP-1068866-A2 Use of mixtures of micropigments for prevening tannig and to induce skin and hair lightening Ciba SC Holding AG (CH) 2001-01-17 EP disclosed
WO-2000078277-A1 MICROPIGMENT MIXTURE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-12-28 WO disclosed
WO-1999066896-A1 SUN SCREEN FORMULATIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-12-29 WO disclosed
EP-0893119-A1 UV-protection formulation Ciba SC Holding AG (CH) 1999-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080247975-A1 Sunscreen and personal care compositions comprising a select copolymer MSH6, CUTA, ERCC5 TDP1 982/4885FFAR3 3869/4885ALDH1A1 1329/4885
US-20100135936-A1 Delivery of hydrophobic benefit agents from bodywashes and the like onto a keratinous substrate KRT18, ABHD16A, CUTA TDP1 3698/4885FFAR3 931/4885ALDH1A1 2300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.