SCHEMBL6265353

SCHEMBL6265353

CCNC(C)=C(CC)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
FFAR3 O14843 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
MMP9 P14780 1/20 0.34
MMP8 P22894 1/20 0.34
KMT2A Q03164 2/20 0.33
THRB P10828 1/20 0.33
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
PGGT1B P53609 1/20 0.33
GRIK1 P39086 2/20 0.32
GRIA4 P48058 1/20 0.32
GRIK3 Q13003 1/20 0.32
GRIK5 Q16478 1/20 0.32
MCL1 Q07820 1/20 0.32
KDM4E B2RXH2 1/20 0.32
FAAH O00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2128891 0.79 EPHX1 (0.45) ALDH1A1MMP1MMP2KMT2ATHRB
SCHEMBL15567984 0.79 EPHX1 (0.45) ALDH1A1MMP1MMP2KMT2ATHRB
SCHEMBL1127391 0.78 TDP1 (0.36) ALDH1A1FFAR3TDP1THRBFNTA
SCHEMBL1127385 0.78 TDP1 (0.36) ALDH1A1FFAR3TDP1THRBFNTA
SCHEMBL10782175 0.77 KMT2A (0.41) ALDH1A1KMT2AFAAH
SCHEMBL5143664 0.76 FFAR3 (0.35) ALDH1A1FFAR3TDP1THRBFNTA
SCHEMBL1275796 0.76 EPHX1 (0.53) ALDH1A1THRBFNTAFNTBPGGT1B
SCHEMBL1275792 0.76 EPHX1 (0.53) ALDH1A1THRBFNTAFNTBPGGT1B
SCHEMBL8055747 0.75 MMP1 (0.37) ALDH1A1FFAR3TDP1MMP1MMP2
SCHEMBL6518333 0.75 MMP1 (0.37) ALDH1A1FFAR3TDP1MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0668958-B1 METHOD FOR CONTROLLING CLATHRATE HYDRATES IN FLUID SYSTEMS COLORADO SCHOOL OF MINES (US) 1998-03-18 EP claimed
CN-113214429-B ArF photoresist film-forming resin, preparation method thereof and photoresist composition 广东粤港澳大湾区黄埔材料研究院 2022-04-12 CN disclosed
CN-113214429-A ArF photoresist film-forming resin, preparation method thereof and photoresist composition 中科院长春应化所黄埔先进材料研究院 2021-08-06 CN disclosed
US-9777024-B2 Heteroaryl inhibitors of PDE4 Tetra Discovery Partners, LLC (US) 2017-10-03 US disclosed
US-20160137672-A1 HETEROARYL INHIBITORS OF PDE4 Tetra Discovery Partners, LLC 2016-05-19 US disclosed
WO-2005035633-A1 CROSSLINKED POLYMER GELS FOR FILTER CAKE FORMATION HALLIBURTON ENERGY SERVICES, INC. (US) 2005-04-21 WO disclosed
US-20050080176-A1 Crosslinked polymer gels for filter cake formation HALLIBURTON ENERGY SERVICES, INC. 2005-04-14 US disclosed
US-20030092584-A1 Deep water completions fracturing fluid compositions BAKER HUGHES INCORPORATED 2003-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160137672-A1 HETEROARYL INHIBITORS OF PDE4 PDE4A, PDE4B, PDE4C ALDH1A1 751/4885FFAR3 1166/4885TDP1 139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.