SCHEMBL1127407

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27959430	0.88	CDK1 (0.50)	ALDH1A1MAPTMEN1KMT2ANPC1
	SCHEMBL1126689	0.77	MAPT (0.59)	ALDH1A1MAPTMEN1KMT2ANPC1
	SCHEMBL1805498	0.72	KDM4E (0.71)	ALDH1A1MAPTLMNAKCNJ1HRH3
	SCHEMBL8329627	0.72	KDM4E (0.71)	ALDH1A1MAPTLMNAKCNJ1HRH3
	SCHEMBL3143167	0.72	KDM4E (0.71)	ALDH1A1MAPTLMNAKCNJ1HRH3
	SCHEMBL12489677	0.70	MAPT (0.85)	ALDH1A1MAPTMEN1KMT2ANPC1
	SCHEMBL2206628	0.70	KDM4E (0.73)	ALDH1A1MAPTNPC1RAB9APOLB
	SCHEMBL3575551	0.70	MAPT (0.56)	PTGS2ALDH1A1MAPTLMNACYP2C9
	SCHEMBL1127034	0.69	MAPT (0.60)	ALDH1A1MAPTMEN1KMT2ANPC1
	SCHEMBL3498032	0.69	CYP11B1 (0.54)	PTGS2ALDH1A1NPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.