SCHEMBL1126689

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27736328	0.83	NPC1 (0.55)	MAPTRAB9ANPC1KMT2AMEN1
	SCHEMBL12489677	0.78	MAPT (0.85)	MAPTRAB9ANPC1KMT2AMEN1
	SCHEMBL1127407	0.77	PTGS2 (0.49)	MAPTRAB9ANPC1KMT2AMEN1
	SCHEMBL1127034	0.76	MAPT (0.60)	MAPTRAB9ANPC1KMT2AMEN1
	SCHEMBL27959430	0.75	CDK1 (0.50)	MAPTRAB9ANPC1KMT2AMEN1
	SCHEMBL4278243	0.75	ALOX15 (0.53)	RAB9ANPC1KMT2AMEN1POLB
	SCHEMBL12490782	0.75	MAPT (1.00)	MAPTRAB9ANPC1KMT2AMEN1
	SCHEMBL7902911	0.73	RAB9A (0.76)	MAPTRAB9ANPC1KMT2AMEN1
	SCHEMBL27714558	0.72	NPC1 (0.52)	MAPTRAB9ANPC1KMT2AMEN1
	SCHEMBL10911272	0.72	KMT2A (0.74)	MAPTRAB9ANPC1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.