Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.44 |
| ▸ | POLB | P06746 | 7/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127114 | 0.73 | L3MBTL1 (0.44) | L3MBTL1TDP1POLBCTDSP1KEAP1 | |
| SCHEMBL1030274 | 0.72 | POLB (0.46) | L3MBTL1TDP1POLBCTDSP1KEAP1 | |
| SCHEMBL15162320 | 0.69 | HSP90AA1 (0.47) | L3MBTL1TDP1POLBCTDSP1KDM4E | |
| SCHEMBL25529106 | 0.68 | L3MBTL1 (0.44) | L3MBTL1TDP1POLBCTDSP1KEAP1 | |
| SCHEMBL2637756 | 0.66 | HSD17B10 (0.48) | L3MBTL1TDP1POLBCTDSP1KDM4E | |
| SCHEMBL18920540 | 0.66 | MYC (0.53) | L3MBTL1TDP1POLBCTDSP1KEAP1 | |
| SCHEMBL5052040 | 0.64 | L3MBTL1 (0.47) | L3MBTL1TDP1POLBCTDSP1KEAP1 | |
| SCHEMBL18920538 | 0.63 | POLB (0.56) | L3MBTL1TDP1POLBCTDSP1KEAP1 | |
| SCHEMBL4395818 | 0.61 | ALDH1A1 (0.50) | L3MBTL1TDP1POLBCTDSP1KEAP1 | |
| SCHEMBL31249455 | 0.60 | ALDH1A1 (0.55) | TDP1KDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |