Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265581 | 0.82 | MAOA (0.44) | TAAR1HTR2AMPOHTR2CHRH1 | |
| SCHEMBL11252069 | 0.81 | SIGMAR1 (0.57) | TAAR1MPOSIGMAR1 | |
| SCHEMBL30464079 | 0.79 | TAAR1 (0.60) | TAAR1HTR2ASIGMAR1HTR2CHTR6 | |
| SCHEMBL4201453 | 0.79 | TAAR1 (0.60) | TAAR1HTR2ASIGMAR1HTR2CHTR6 | |
| SCHEMBL20615042 | 0.78 | CHRM2 (0.52) | TAAR1HTR2ASLC6A2DRD2MPO | |
| SCHEMBL2903629 | 0.78 | TAAR1 (0.59) | TAAR1HTR2ASLC6A2SIGMAR1HTR2C | |
| SCHEMBL22762073 | 0.77 | TAAR1 (0.63) | TAAR1HTR2ASLC6A2DRD2SIGMAR1 | |
| SCHEMBL172293 | 0.77 | TAAR1 (0.63) | TAAR1MPO | |
| SCHEMBL22638728 | 0.76 | MPO (0.64) | TAAR1HTR2AMPOSIGMAR1 | |
| SCHEMBL4181180 | 0.75 | TAAR1 (0.56) | TAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360511-A | Amines useful as brain imaging agents | MEDI-PHYSICS, INC. (US) | 1982-11-23 | — | — | US | disclosed |