Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283760 | 0.85 | ALDH1A1 (0.36) | CYP1A2CYP3A4CYP2C19ALDH1A1KDM4E | |
| SCHEMBL11270977 | 0.77 | MAPT (0.40) | CYP1A2CYP3A4CYP2C19ALDH1A1KDM4E | |
| SCHEMBL11273764 | 0.72 | PLK1 (0.33) | CYP1A2CYP2C19ALDH1A1KDM4EPLK1 | |
| SCHEMBL11273839 | 0.71 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2C19ALDH1A1KDM4E | |
| SCHEMBL11268181 | 0.71 | CYP1A2 (0.51) | CYP1A2CYP3A4CYP2C19ALDH1A1KDM4E | |
| SCHEMBL5969858 | 0.71 | TNKS (0.54) | CYP3A4ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL11267104 | 0.70 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C19ALDH1A1KDM4E | |
| SCHEMBL755139 | 0.70 | KDM4E (0.61) | ALDH1A1KDM4EHTTLMNAHPGD | |
| SCHEMBL3378970 | 0.69 | PRKDC (0.38) | CYP1A2CYP3A4CYP2C19ALDH1A1KDM4E | |
| SCHEMBL6060851 | 0.69 | KDM4E (0.36) | CYP1A2CYP3A4CYP2C19ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316904-A | Indolopyrone tetrazoles and carboxamidotetrazoles having antiallergic activity | WARNER-LAMBERT COMPANY | 1982-02-23 | — | — | US | disclosed |