Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 5/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241714 | 0.88 | LMNA (0.47) | LMNABACE1CTSDOPRM1OPRL1 | |
| SCHEMBL11291814 | 0.86 | LMNA (0.48) | LMNABACE1CTSDOPRM1OPRL1 | |
| SCHEMBL11287581 | 0.85 | HTR1A (0.44) | LMNABACE1CTSDGRIN2BALDH1A1 | |
| SCHEMBL11285044 | 0.84 | LMNA (0.47) | LMNABACE1CTSDOPRM1OPRL1 | |
| SCHEMBL11287989 | 0.84 | ALDH1A1 (0.44) | LMNABACE1CTSDTRPV1ALDH1A1 | |
| SCHEMBL11293265 | 0.81 | LMNA (0.47) | LMNABACE1CTSDTRPV1GRIN2B | |
| SCHEMBL11481567 | 0.79 | TRPV1 (0.40) | LMNABACE1CTSDOPRM1TRPV1 | |
| SCHEMBL11281586 | 0.79 | LMNA (0.44) | LMNABACE1CTSDOPRM1OPRL1 | |
| SCHEMBL11273325 | 0.78 | LMNA (0.43) | LMNABACE1CTSDGRIN2BALDH1A1 | |
| SCHEMBL11250576 | 0.77 | KMT2A (0.38) | LMNABACE1CTSDTRPV1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001428-B1 | INSECTICIDAL AND ACARICIDAL AGENTS CONTAINING CHROMAN DERIVATIVES, THEIR PREPARATION AND THEIR USE, AS WELL AS CHROMAN DERIVATIVES AND THEIR PREPARATION | BAYER AG (DE) | 1982-03-24 | — | — | EP | disclosed |
| US-4238501-A | INSECTICIDES, MITICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
| US-4237162-A | MITICIDES, LARVACIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-02 | — | — | US | disclosed |
| EP-0001428-A1 | Insecticidal and acaricidal agents containing chroman derivatives, their preparation and their use, as well as chroman derivatives and their preparation | BAYER AG (DE) | 1979-04-18 | — | — | EP | disclosed |