Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | BACE1 | P56817 | 5/20 | 0.44 |
| ▸ | CTSD | P07339 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239322 | 0.89 | BACE1 (0.45) | LMNABACE1CTSDTP53HTT | |
| SCHEMBL11291814 | 0.87 | LMNA (0.48) | LMNABACE1CTSDGRIN2BTRPV1 | |
| SCHEMBL11285044 | 0.86 | LMNA (0.47) | LMNABACE1CTSDGRIN2BTRPV1 | |
| SCHEMBL11281586 | 0.83 | LMNA (0.44) | LMNABACE1CTSDTP53HTT | |
| SCHEMBL11273325 | 0.82 | LMNA (0.43) | LMNABACE1CTSDHTTGRIN2B | |
| SCHEMBL11275339 | 0.81 | LMNA (0.55) | LMNABACE1CTSDHTTGRIN2B | |
| SCHEMBL11248305 | 0.81 | OPRD1 (0.42) | LMNABACE1CTSDGRIN2BTRPV1 | |
| SCHEMBL11287989 | 0.81 | ALDH1A1 (0.44) | LMNABACE1CTSDSMN1; SMN2NPSR1 | |
| SCHEMBL11481607 | 0.80 | BACE1 (0.40) | LMNABACE1CTSDTP53HTT | |
| SCHEMBL11486948 | 0.78 | TRPV1 (0.43) | LMNABACE1CTSDTRPV1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001428-B1 | INSECTICIDAL AND ACARICIDAL AGENTS CONTAINING CHROMAN DERIVATIVES, THEIR PREPARATION AND THEIR USE, AS WELL AS CHROMAN DERIVATIVES AND THEIR PREPARATION | BAYER AG (DE) | 1982-03-24 | — | — | EP | disclosed |
| US-4238501-A | INSECTICIDES, MITICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
| US-4237162-A | MITICIDES, LARVACIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-02 | — | — | US | disclosed |
| EP-0001428-A1 | Insecticidal and acaricidal agents containing chroman derivatives, their preparation and their use, as well as chroman derivatives and their preparation | BAYER AG (DE) | 1979-04-18 | — | — | EP | disclosed |