SCHEMBL11275836

SCHEMBL11275836

COC(=O)CN(C(=O)CSC(=O)C(C)C)c1c(C)cccc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.38
MEN1 O00255 1/20 0.38
PLA2G1B P04054 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
MLYCD O95822 1/20 0.36
ALDH1A1 P00352 7/20 0.36
TP53 P04637 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
CYP3A4 P08684 2/20 0.36
RXFP1 Q9HBX9 2/20 0.35
HSD17B10 Q99714 2/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35
TSHR P16473 2/20 0.34
USP2 O75604 1/20 0.34
PRNP P04156 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11272283 0.89 ALDH1A1 (0.34) NPSR1MEN1PLA2G1BHTTKMT2A
SCHEMBL11275039 0.89 MLYCD (0.36) NPSR1MEN1PLA2G1BHTTKMT2A
SCHEMBL11271761 0.88 ALDH1A1 (0.34) NPSR1MEN1PLA2G1BHTTKMT2A
SCHEMBL11290774 0.87 ALDH1A1 (0.36) NPSR1MEN1PLA2G1BHTTKMT2A
SCHEMBL11278423 0.85 HDAC6 (0.34) NPSR1MEN1PLA2G1BHTTKMT2A
SCHEMBL11284341 0.85 RAB9A (0.39) MEN1HTTKMT2AMLYCDALDH1A1
SCHEMBL11273473 0.85 MLYCD (0.33) MLYCDALDH1A1TDP1HPGDRAB9A
SCHEMBL11272346 0.84 ALDH1A1 (0.39) ALDH1A1TP53TDP1CYP3A4RXFP1
SCHEMBL11280635 0.82 ALDH1A1 (0.35) ALDH1A1TP53TDP1CYP3A4RXFP1
SCHEMBL11279587 0.82 ALDH1A1 (0.35) NPSR1MEN1HTTKMT2AMLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4313957-A Pesticidal sulfur containing amides derived from aniline and the method of preparation thereof RHONE-POULENC AGROCHIMIE (FR) 1982-02-02 US disclosed