SCHEMBL11284341

SCHEMBL11284341

COC(=O)CN(C(=O)CSC(=O)C(C)C)c1c(C)ccc(Cl)c1C

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.39
ALDH1A1 P00352 3/20 0.34
MAPT P10636 3/20 0.34
KDM4E B2RXH2 1/20 0.34
MLYCD O95822 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
PKM P14618 1/20 0.32
ALOX15 P16050 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11275039 0.91 MLYCD (0.36) RAB9AALDH1A1MLYCDMEN1KMT2A
SCHEMBL11283176 0.90 RAB9A (0.37) RAB9AALDH1A1MAPTKDM4EMEN1
SCHEMBL11279890 0.89 RAB9A (0.38) RAB9AALDH1A1MAPTKDM4EMEN1
SCHEMBL11299749 0.89 SMN1; SMN2 (0.34) ALDH1A1MAPTMEN1KMT2APKM
SCHEMBL11277898 0.87 RAB9A (0.41) RAB9AALDH1A1MAPTKDM4EMEN1
SCHEMBL11276489 0.87 RAB9A (0.38) RAB9AALDH1A1MAPTKDM4EMLYCD
SCHEMBL11273473 0.87 MLYCD (0.33) RAB9AALDH1A1MLYCD
SCHEMBL11271232 0.86 RAB9A (0.40) RAB9AALDH1A1MAPTKDM4EMEN1
SCHEMBL11275836 0.85 NPSR1 (0.38) RAB9AALDH1A1MAPTMLYCDMEN1
SCHEMBL11285126 0.84 RAB9A (0.39) RAB9AALDH1A1MAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4313957-A Pesticidal sulfur containing amides derived from aniline and the method of preparation thereof RHONE-POULENC AGROCHIMIE (FR) 1982-02-02 US disclosed