Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | ASPH | Q12797 | 1/20 | 0.44 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27554852 | 0.84 | SMN1; SMN2 (0.38) | KDM4EASPHKDM8ALDH1A1SMN1; SMN2 | |
| SCHEMBL15991433 | 0.82 | SIRT3 (0.43) | KDM4EALDH1A1SMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL26987484 | 0.79 | KDM4E (0.45) | KDM4EALDH1A1TDP1LMNAMAPT | |
| SCHEMBL31184683 | 0.79 | KDM4E (0.45) | KDM4EALDH1A1TDP1LMNAMAPT | |
| SCHEMBL14335806 | 0.79 | KDM4E (0.52) | KDM4EASPHKDM8ALDH1A1SMN1; SMN2 | |
| SCHEMBL353106 | 0.79 | KDM4E (0.47) | KDM4EASPHKDM8ALDH1A1SMN1; SMN2 | |
| SCHEMBL1767848 | 0.78 | KDM4E (0.46) | KDM4EASPHKDM8ALDH1A1SMN1; SMN2 | |
| SCHEMBL19857487 | 0.78 | KDM4E (0.60) | KDM4EASPHKDM8ALDH1A1L3MBTL1 | |
| SCHEMBL27101555 | 0.77 | KDM4E (0.42) | KDM4EASPHKDM8ALDH1A1SMN1; SMN2 | |
| SCHEMBL23500918 | 0.76 | SMN1; SMN2 (0.46) | KDM4EASPHKDM8ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4646402-A1 | GPR35 MODULATORS | ThirtyFiveBio Limited (GB) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024147009-A1 | GPR35 MODULATORS | ThirtyFiveBio Limited (GB) | 2024-07-11 | — | — | WO | disclosed |
| US-9695162-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20170029416-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2017-02-02 | — | — | US | disclosed |
| US-20170029406-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | ATTUNE PHARMACEUTICALS, INC. | 2017-02-02 | — | — | US | disclosed |
| US-9475803-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2016-10-25 | — | — | US | disclosed |
| US-20150376176-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2015-12-31 | — | — | US | disclosed |
| WO-2014130513-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2014-08-28 | — | — | WO | disclosed |
| EP-2424843-B1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF CYCLIN DEPENDENT KINASES | NOVARTIS AG (CH) | 2014-03-26 | — | — | EP | disclosed |
| US-8598217-B2 | Imidazole derivatives and their use as modulators of cyclin dependent kinases | ASTEX THERAPEUTICS LTD. (GB) | 2013-12-03 | — | — | US | disclosed |
| US-20120101064-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF CYCLIN DEPENDENT KINASES | ASTEX THERAPEUTICS LIMITED (GB) | 2012-04-26 | — | — | US | disclosed |
| EP-2424843-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF CYCLIN DEPENDENT KINASES | Novartis AG (CH) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010125402-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF CYCLIN DEPENDENT KINASES | NOVARTIS AG (CH) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170029406-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | KLKB1, SERPINB1, SERPINE1 | KDM4E 798/4885ASPH 1170/4885KDM8 125/4885 |
| US-20120101064-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF CYCLIN DEPENDENT KINASES | CDK3, CCNI, CDK1 | KDM4E 1090/4885ASPH 2180/4885KDM8 484/4885 |
| US-20150376176-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | KDM4E 1800/4885ASPH 1335/4885KDM8 4248/4885 |
| US-20170029416-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | KDM4E 1996/4885ASPH 1251/4885KDM8 4361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.