SCHEMBL1127609

SCHEMBL1127609

C=C(CCl)C(=O)OCCN(CC)CC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRCP P42785 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
CYP2D6 P10635 2/20 0.41
LMNA P02545 2/20 0.41
MAOA P21397 2/20 0.41
HTR3A P46098 2/20 0.41
HRH3 Q9Y5N1 2/20 0.41
CYP1A2 P05177 1/20 0.41
TSHR P16473 1/20 0.41
ALDH1A1 P00352 3/20 0.40
POLB P06746 2/20 0.40
BLM P54132 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
CYP3A4 P08684 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CHRM2 P08172 4/20 0.39
CHRM3 P20309 3/20 0.39
CHRM1 P11229 2/20 0.39
SCN1A P35498 1/20 0.39
SCN2A Q99250 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2876431 0.90 ALDH1A1 (0.44) CYP2D6LMNAHTR3AHRH3CYP1A2
SCHEMBL9546035 0.89 SIGMAR1 (0.43) PRCPSIGMAR1CYP2D6LMNAMAOA
SCHEMBL10457624 0.84 PRCP (0.42) PRCPSIGMAR1CYP2D6LMNAMAOA
SCHEMBL127031 0.81 CHRM1 (0.48) SIGMAR1LMNAMAOAHRH3CYP1A2
SCHEMBL11249504 0.81 SIGMAR1 (0.43) PRCPSIGMAR1CYP2D6LMNAMAOA
SCHEMBL25380908 0.80 LMNA (0.50) SIGMAR1CYP2D6LMNAMAOAHTR3A
SCHEMBL28055236 0.80 CHRM1 (0.47) SIGMAR1LMNAMAOAHRH3CYP1A2
Ammonia Solution, Strong SCHEMBL28118760 0.80 CHRM1 (0.47) SIGMAR1LMNAMAOAHRH3CYP1A2
Chloromethane SCHEMBL1128072 0.80 THRB (0.52) SIGMAR1CYP2D6LMNAMAOAHTR3A
SCHEMBL14874 0.79 THRB (0.55) SIGMAR1CYP2D6LMNAMAOAHTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023154839-A1 HIGH MOLECULAR WEIGHT GPAM WITH ANIONIC POLYMERIC PROMOTER KEMIRA OYJ (FI) 2023-08-17 WO claimed
WO-2023154840-A1 HIGH MOLECULAR WEIGHT GPAM WITH ANIONIC POLYSACCHARIDE PROMOTER KEMIRA OYJ (FI) 2023-08-17 WO claimed
EP-2109441-B1 POLYSILOXANE BLOCK COPOLYMERS BASF SE (DE) 2016-01-27 EP claimed
US-8378038-B2 Polysiloxane block copolymers BASF SE (DE) 2013-02-19 US claimed
US-8273216-B2 Process for the production of paper AKZO NOBEL N.V. (NL) 2012-09-25 US claimed
US-8148318-B2 Home or fabric care compositions comprising certain dye-polymer complexes BASF SE (DE) 2012-04-03 US claimed
US-8147814-B2 Personal care compositions comprising certain dye-polymer complexes BASF SE (DE) 2012-04-03 US claimed
US-20100303750-A1 POLYSILOXANE BLOCK COPOLYMERS KOROSKENYI BALINT 2010-12-02 US claimed
US-7732525-B2 Polymers for paper and paperboard coatings CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) 2010-06-08 US claimed
EP-2109441-A2 POLYSILOXANE BLOCK COPOLYMERS Ciba Holding Inc. (CH) 2009-10-21 EP claimed
EP-2046932-A2 COMPOSITION FOR IMPROVING WETTABILITY OF SURFACES Ciba Holding Inc. (CH) 2009-04-15 EP claimed
US-20080199418-A1 Polysiloxane block copolymers BASF SE (DE) 2008-08-21 US claimed
WO-2008095822-A2 POLYSILOXANE BLOCK COPOLYMERS CIBA HOLDING INC. (CH) 2008-08-14 WO claimed
US-20080033106-A1 Composition for improving wettability of surfaces CIBA SPECIALTY CHEMICALS CORP. 2008-02-07 US claimed
WO-2008015138-A2 COMPOSITION FOR IMPROVING WETTABILITY OF SURFACES CIBA HOLDING INC. (CH) 2008-02-07 WO claimed
WO-2001027173-A1 CATIONIC LATEX TERPOLYMERS FOR WASTEWATER TREATMENT NALCO CHEMICAL COMPANY (US) 2001-04-19 WO claimed
CN-114206955-B Method for controlling the production of excess water and aqueous fluids in oil and gas wells 能源解决方案(美国)有限责任公司 2024-01-30 CN disclosed
CN-116829675-A Inversion surfactant for inverse emulsion 能源解决方案(美国)有限责任公司 2023-09-29 CN disclosed
WO-2001027173-A1 CATIONIC LATEX TERPOLYMERS FOR WASTEWATER TREATMENT NALCO CHEMICAL COMPANY (US) 2001-04-19 WO disclosed
WO-2001027173-A1 CATIONIC LATEX TERPOLYMERS FOR WASTEWATER TREATMENT NALCO CHEMICAL COMPANY (US) 2001-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100303750-A1 POLYSILOXANE BLOCK COPOLYMERS KRT18, PUF60, SCNN1B PRCP 4044/4885SIGMAR1 2460/4885CYP2D6 4277/4885
US-20080199418-A1 Polysiloxane block copolymers KRT18, PUF60, SCNN1B PRCP 4044/4885SIGMAR1 2460/4885CYP2D6 4277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.