Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CD44 | P16070 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20012353 | 0.88 | SKP2 (0.46) | SKP2ALDH1A1TLR8CYP3A4TYR | |
| SCHEMBL18428550 | 0.85 | ALOX5 (0.47) | TLR8CYP3A4TYRALOX5TSHR | |
| SCHEMBL13375177 | 0.85 | ALDH1A1 (0.48) | SKP2ALDH1A1CYP3A4TSHRTP53 | |
| SCHEMBL29739851 | 0.85 | ALOX5 (0.47) | TLR8CYP3A4TYRALOX5TSHR | |
| SCHEMBL14681822 | 0.85 | ALOX5 (0.47) | TLR8CYP3A4TYRALOX5TSHR | |
| SCHEMBL840888 | 0.85 | ALOX5 (0.47) | TLR8CYP3A4TYRALOX5TSHR | |
| SCHEMBL23093069 | 0.83 | ALDH1A1 (0.59) | SKP2ALDH1A1TLR8CYP3A4TYR | |
| SCHEMBL11114074 | 0.82 | TLR8 (0.46) | SKP2TLR8CYP3A4TYRALOX5 | |
| SCHEMBL20816041 | 0.82 | ALOX5 (0.48) | ALDH1A1CYP3A4TYRALOX5TSHR | |
| Hydrochloric Acid SCHEMBL10861940 | 0.82 | ALOX5 (0.47) | ALDH1A1CYP3A4TYRALOX5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344957-A | Benz-acyl-benzimidazole derivatives and antiallergic compositions | CIBA-GEIGY CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |