Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277920 | 0.90 | KLK7 (0.47) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL11268529 | 0.88 | ALDH1A1 (0.43) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL11276136 | 0.86 | LMNA (0.48) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL11274624 | 0.85 | KMT2A (0.55) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL11273842 | 0.85 | KMT2A (0.48) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL11272855 | 0.84 | KMT2A (0.46) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL11427666 | 0.82 | KMT2A (0.49) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL11270219 | 0.81 | KMT2A (0.49) | KMT2AMEN1MAPTALDH1A1ATM | |
| SCHEMBL11272853 | 0.81 | KMT2A (0.46) | KMT2AMEN1MAPTKDM4ELMNA | |
| SCHEMBL11276142 | 0.81 | KMT2A (0.38) | KMT2AMEN1MAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310533-A | INHIBITING PLASMIN AND-OR TRYSIN ACTIVITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-01-12 | — | — | US | disclosed |