Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | ACR | P10323 | 2/20 | 0.38 |
| ▸ | F7 | P08709 | 4/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268529 | 0.88 | ALDH1A1 (0.43) | KMT2APRSS1ACRSMN1; SMN2MEN1 | |
| SCHEMBL11273835 | 0.86 | KMT2A (0.40) | KMT2APRSS1ACRF7F2 | |
| SCHEMBL11274623 | 0.85 | RECQL (0.49) | KMT2APRSS1ACRF7F2 | |
| SCHEMBL11276133 | 0.85 | L3MBTL1 (0.46) | KMT2AF7F2MEN1ALDH1A1 | |
| SCHEMBL11272851 | 0.85 | MGLL (0.43) | KMT2APRSS1ACRSMN1; SMN2MEN1 | |
| SCHEMBL9235998 | 0.84 | ACR (0.40) | KMT2APRSS1ACRF2F10 | |
| SCHEMBL9231748 | 0.84 | ACR (0.40) | KMT2APRSS1ACRF2F10 | |
| Methane SCHEMBL9230653 | 0.83 | KMT2A (0.41) | KMT2APRSS1ACRF7F2 | |
| SCHEMBL11427664 | 0.83 | KMT2A (0.50) | KMT2APRSS1ACRSMN1; SMN2MEN1 | |
| SCHEMBL11277920 | 0.83 | KLK7 (0.47) | KMT2APRSS1F2SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310533-A | INHIBITING PLASMIN AND-OR TRYSIN ACTIVITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-01-12 | — | — | US | disclosed |