Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277920 | 0.90 | KLK7 (0.47) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL11276148 | 0.88 | KMT2A (0.42) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL11272864 | 0.88 | KMT2A (0.46) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL11272853 | 0.88 | KMT2A (0.46) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL11276142 | 0.88 | KMT2A (0.38) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL1648216 | 0.84 | KMT2A (0.47) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL11277772 | 0.83 | MEN1 (0.55) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL11277441 | 0.83 | HPGD (0.58) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL11267592 | 0.83 | KMT2A (0.47) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11277245 | 0.82 | MGLL (0.48) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310533-A | INHIBITING PLASMIN AND-OR TRYSIN ACTIVITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-01-12 | — | — | US | disclosed |