Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11282166 | 0.83 | KMT2A (0.54) | ALDH1A1KMT2AHSD17B10LMNA | |
| SCHEMBL5216927 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KMT2AKDM4EGAAKCNA5 | |
| SCHEMBL30430689 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KMT2AKDM4EGAAKCNA5 | |
| Hydrochloric Acid SCHEMBL15270291 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KMT2AKDM4EGAAKCNA5 | |
| SCHEMBL11487828 | 0.78 | SMN1; SMN2 (0.50) | ALDH1A1GAAKCNA5POLBCYP17A1 | |
| SCHEMBL6776942 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KMT2AKDM4EGAAKCNA5 | |
| SCHEMBL11276726 | 0.74 | HPGDS (0.34) | ALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL9313982 | 0.74 | ALDH1A1 (0.51) | ALDH1A1KMT2AKDM4EGAAKCNA5 | |
| SCHEMBL28520217 | 0.73 | ALDH1A1 (0.45) | ALDH1A1KMT2AKDM4EGAAKCNA5 | |
| SCHEMBL5966871 | 0.73 | RAB9A (0.43) | ALDH1A1KCNA5POLBCYP17A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344956-A | Oxotetrahydrothiophenes | ERCOLI NICOLO | 1982-08-17 | — | — | US | disclosed |