Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269036 | 0.85 | MMP8 (0.46) | KMT2ATSHRMEN1LMNA | |
| SCHEMBL11276514 | 0.83 | ALDH1A1 (0.40) | KMT2AHSD17B10ALDH1A1LMNA | |
| SCHEMBL318862 | 0.79 | KMT2A (0.64) | KMT2ATSHRCYP2D6CYP3A4CYP1A2 | |
| SCHEMBL283419 | 0.79 | KMT2A (0.64) | KMT2ATSHRCYP2D6CYP3A4CYP1A2 | |
| SCHEMBL318460 | 0.79 | KMT2A (0.64) | KMT2ATSHRCYP2D6CYP3A4CYP1A2 | |
| SCHEMBL29841724 | 0.79 | KMT2A (0.64) | KMT2ATSHRCYP2D6CYP3A4CYP1A2 | |
| Hydrochloric Acid SCHEMBL1143309 | 0.78 | KMT2A (0.62) | KMT2ATSHRCYP2D6CYP3A4CYP1A2 | |
| Hydrochloric Acid SCHEMBL852494 | 0.78 | KMT2A (0.62) | KMT2ATSHRCYP2D6CYP3A4CYP1A2 | |
| Hydrochloric Acid SCHEMBL852495 | 0.78 | KMT2A (0.62) | KMT2ATSHRCYP2D6CYP3A4CYP1A2 | |
| SCHEMBL11282608 | 0.78 | KMT2A (0.38) | KMT2AMEN1ALDH1A1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344956-A | Oxotetrahydrothiophenes | ERCOLI NICOLO | 1982-08-17 | — | — | US | disclosed |