Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12777592 | 0.97 | NLRP3 (0.41) | PTGS2POLBKDM4EMAPTALOX15 | |
| SCHEMBL14752782 | 0.84 | MAPT (0.40) | POLBKDM4EMAPTALOX15MEN1 | |
| SCHEMBL4492930 | 0.82 | MAPT (0.43) | POLBKDM4EMAPTALOX15MEN1 | |
| SCHEMBL13712262 | 0.78 | SLC26A6 (0.42) | KDM4EMAPTALOX15MEN1KMT2A | |
| SCHEMBL8120086 | 0.78 | ALDH1A1 (0.49) | KDM4EMAPTALOX15MEN1KMT2A | |
| SCHEMBL5657293 | 0.78 | ALDH1A1 (0.44) | POLBKDM4EMAPTALOX15MEN1 | |
| SCHEMBL13374643 | 0.78 | MAPT (0.42) | KDM4EMAPTALOX15MEN1KMT2A | |
| SCHEMBL234027 | 0.77 | KDM4E (0.55) | POLBKDM4EMAPTALOX15MEN1 | |
| SCHEMBL4495971 | 0.77 | MAPT (0.44) | POLBKDM4EMAPTALOX15MEN1 | |
| SCHEMBL5657803 | 0.76 | ALDH1A1 (0.43) | KDM4EMAPTALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315939-A | Piperidine derivatives of 4,5-dialkyl-3-hydroxy-pyrrole-2-carboxylic acid esters, pharmaceutical formulations containing these compounds and use in treating cardiac arrhythmias | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | disclosed |